When it comes to Survivor Week 1, I always play the best game on the board (for one pick) and mix the best team in heavily for multiple picks (50% usage as I indicated here for my 20 picks). My reasoning is this: We really don't know who is going to shake out as the "top 17 teams" without seeing any game play. Who is going to be the hot ten teams? Who is going to lose a top player (or have one not show up, a la Pittsburgh)? These are all questions yet to be answered. I don't know who I will play in Week 2 until I've seen all 16 games this week. What I do know, is it is all meaningless preparing for "who do I pick in Week 2" if I lose in Week 1. I don't start mapping out tickets until after 4 games, and then I try to create a path to victory for each ticket I have left. And then I have to usually adjust those every single week as teams rise and fall, and matchups look better or worse.
In summation, my approach for the first few weeks is to "take the strongest candidate to win straight up" and then worry about crossing the next bridge if you survive.
Later on, those tickets with the "big dogs" still available become very valuable. But ya gotta get there first. In my case, I have New Orleans "saved for later" on half my tickets. I think that's a reasonable approach.
And for those with one ticket, for instance my 250k FanDuel Survivor is New Orleans, because I want to Survive.